The Human Upgrade with Dave Asprey

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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.

You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.

Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.

Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 

Recent Episodes
  • The Secret Molecule for Endless Energy | Dr. Andrew Salzman : 1253
    Feb 21, 2025 – 01:24:01
  • Fix Your Blood Sugar: The FASTEST Way to Burn Fat, Optimize Hormones & Reverse Disease | Benjamin Bikman : 1252
    Feb 20, 2025 – 01:20:08
  • Rick Rubin: How to Hack Your Mind for Creative Breakthroughs : 1251
    Feb 18, 2025 – 00:54:51
  • Tony Robbins on the Ultimate Secrets to Wealth, Mindset, and Success : 1250
    Feb 13, 2025 – 00:56:49
  • Timbaland's Blueprint: How to Lose 130 Pounds, Beat Addiction, and Change Your Life TODAY! : 1249
    Feb 11, 2025 – 00:40:01
  • Gary Brecka: The SECRET Blood Marker That Could Save Your Life! (pt. 2) : 1248
    Feb 6, 2025 – 01:02:00
  • Gary Brecka: The World Is KILLING You—Use AI To Restore Testosterone, Energy & Longevity (Pt. 1) : 1247
    Feb 5, 2025 – 00:37:24
  • Ancient Secrets THEY Hid from You (That Still Work Today!) – Lost Technology, The Pyramid Code, and Quantum Reality | Billy Carson (Harvard & MIT) & Elisabeth Carson : 1246
    Jan 30, 2025 – 01:40:25
  • Stop Counting Calories! Diet Myths Exposed (And What to Do Instead) | Dr. Nick Norwitz : 1245
    Jan 28, 2025 – 01:27:57
  • How to Hack Your Stress and Engineer Your Tears to BOOST Longevity | Jeff Krasno : 1244
    Jan 23, 2025 – 01:34:40
  • 2025 Biohacking State of the Union: Master Supplementation Guide with Dr. Sandra Kaufmann : 1243
    Jan 21, 2025 – 01:29:21
  • How to Be a Real-Life DR. STRANGE with These 8 Ancient Secrets for Healing | Barry Morguelan : 1242
    Jan 16, 2025 – 01:07:15
  • Add Decades to Your Life with THESE AI Tools and Longevity Secrets! Peter Diamandis : 1241
    Jan 14, 2025 – 01:19:47
  • Improve your Vision Forever with These Three FREE Exercises | Dr. Bryce Appelbaum : 1240
    Jan 9, 2025 – 00:57:36
  • Try These Age-Reversing Plants to Turn Back Time! How to LIVE to 250 with Christian Drapeau : 1239
    Jan 7, 2025 – 00:55:44
  • The TRUTH About Vaccines for Kids (A Pediatrician Speaks Out on the Risks) | Joel "Gator" Warsh : 1238
    Jan 2, 2025 – 01:26:10
  • How to Gain SUPERHUMAN Hearing (With Very Little Effort!) Brandon Sawalich : 1237
    Dec 31, 2024 – 00:46:56
  • How to STOP Living in Fear and Find Your Purpose in Life | Ryan Holiday : 1236
    Dec 26, 2024 – 01:15:30
  • Ditch the 10,000-Hour Rule & Escape Failure Porn for RAPID Success | James Altucher : 1235
    Dec 24, 2024 – 00:57:27
  • How to HACK Your HATE with Daryl Davis (The Jazz Musician Who Defeated the KKK) : 1234
    Dec 19, 2024 – 01:29:55
  • Why 50% of Us Won’t Live Past 76—And How to Beat the Odds. Pradeep Albert : 1233
    Dec 17, 2024 – 01:21:25
  • Here’s How to Get the ULTIMATE Liver (And Why It Will Change Your Life!) Siggi Clavien : 1232
    Dec 13, 2024 – 01:08:51
  • Ex Google-Exec: AI is Going to Kill Us in 2027. (Only to Make us Happier!) | Mo Gawdat (Part 2) : 1231
    Dec 12, 2024 – 00:23:58
  • How Google X’s Mo Gawdat Made 1 Billion People Happier - Including YOU (Part 1) : 1230
    Dec 10, 2024 – 01:06:59
  • Is Red Meat the Fountain of Youth? Paul Saladino : 1229
    Dec 5, 2024 – 01:43:01
  • Why is your Oral Health KILLING you, and what can you do about it?! Naveen Jain : 1228
    Dec 3, 2024 – 01:10:57
  • What You DON'T Know About Women’s Health! From Microbiome to Major Impact with Priyanka Jain : 1227
    Nov 28, 2024 – 01:12:06
  • The World’s BEST Alcohol Alternative. Pleasure, Relaxation, and Clarity with TRU KAVA : 1226
    Nov 26, 2024 – 01:07:18
  • Urolithin A’s Secret to YOUTHFUL ENERGY and the Fight Against Inflammaging : 1225
    Nov 22, 2024 – 00:58:46
  • Exosomes vs Stem Cells and LIFE-CHANGING Advice with Harvard Physician Dr. Edward Park : 1224
    Nov 21, 2024 – 01:11:01
  • Is Infrared Light the KEY to Longevity? Detox, Recovery, and Increased Energy with Sunlighten Saunas : 1223
    Nov 19, 2024 – 00:49:51
  • How to Discover What You TRULY Want—and Ask for It! Featuring the Author of Dave’s Top Book for Women : 1222
    Nov 14, 2024 – 01:45:53
  • How to Optimize Your Brain for WORK: Achieving Hyper-Efficiency with Dr. Mithu Storoni : 1221
    Nov 12, 2024 – 01:24:02
  • Tim Ferriss: Smart Drugs, Insect Protein, Sex, and His 3 Top Tips for a SUCCESSFUL Life : 1220
    Nov 7, 2024 – 00:34:23
  • Happiness Hacks That Actually Work (And What You’re Getting Wrong) with the World’s Leading Happiness Expert: Arthur Brooks : 1219
    Nov 5, 2024 – 01:18:27
  • Learn How to HACK Your Mind with Hypnosis: The Ultimate Cognitive Upgrade : 1218
    Oct 31, 2024 – 00:59:53
  • Dave Asprey’s FULL Masterclass on Cognitive Enhancement : 1217
    Oct 29, 2024 – 01:20:29
  • How to DETOX Like a Pro! Phosphatidylcholine, Tudca, and Butyrate for Maximum Cellular Cleansing : 1216
    Oct 25, 2024 – 01:04:29
  • Steroids, Gene Therapy, Peptides: The Future of ENHANCED Sports with Aron D’Souza : 1215
    Oct 24, 2024 – 01:07:39
  • Why and HOW to Biohack Your Blood Glucose Levels 24/7 : 1214
    Oct 22, 2024 – 01:23:36
  • The Superfood Algae that WILL change your life! : 1213
    Oct 18, 2024 – 00:58:54
  • Discover the Purpose of Life: Mastering Emotional Intelligence with the Demartini Method : 1212
    Oct 17, 2024 – 01:10:00
  • Don’t Die with Bryan Johnson : 1211
    Oct 15, 2024 – 01:21:33
  • VO2 Max and Mitochondria Mastery: Biohacking with the NanoVi : 1210
    Oct 11, 2024 – 00:39:01
  • Transform Your Home into a Biohacker’s Dream: Expert Tips for Ultimate Health Optimization : 1209
    Oct 10, 2024 – 00:59:47
  • Dr. Andrew Huberman: Neuroscience Hacks for Peak Brain Performance and Stress Mastery : 1208
    Oct 8, 2024 – 01:00:42
  • Unlock Heart Health: Top Cardiologist Reveals Groundbreaking Natural Hacks : 1207
    Oct 3, 2024 – 00:55:16
  • Sleep Smarter, Live Longer: Matthew Walker and Sleep Experts share Secrets to Better Sleep Performance : 1206
    Oct 1, 2024 – 01:02:56
  • Unlock the Master Molecule: Glutaryl for Superior Detox, Skin, and Energy : 1205
    Sep 27, 2024 – 00:48:45
  • Sexual Mastery with the World’s Top Experts: Unlocking Pleasure, Performance, and Intimacy : 1204
    Sep 26, 2024 – 01:01:53
Recent Reviews
  • Doug and Kate
    Wow! Asprey/Brecka Master class
    I’ve been on my healing journey for five years. I’ve read over 140 books on cellular healing and biohacking and follow the podcasts of both Asprey and Brecka for years. This two-part interview is the best. Well done, gents.
  • Heidi431
    Sounds smug and just trying to sell you stuff
    Host talks over guests and it’s annoying. Many of the episodes are just long commercials.
  • michaelthomascallahan
    Too niche
    Not for me. Way too in the weeds, and the host comes across as elite.
  • appifyyyy
    Great podcast
    Long time follower and avid biohacker myself. The more I become entrenched in biohacking, the more open minded, curious and spiritual I become. The episode with the Carson’s was a great listen and it’s refreshing to see someone with such a scientific mind be not only open to these discussions, but also heavily involved.
  • Utahpia
    Dr B
    Thank you Dave! As always you bring the most incredible insights. Dr Barry Morguelan rounds out another amazing practice that I will be implementing into my life. 🙏 Again, thank you both!
  • Zed8257
    Not a good host
    Interesting guests on the show that I’d definitely come back to listen to, but awful host. Started with the Bryan Johnson episode and I agree with other reviews Dave is so disrespectful and does a terrible job of asking vulnerable questions, I was uncomfortable listening to it.
  • KaitlinBeManifesting
    Interesting Science paired either a touch of humor
    Highly recommend! Dave has a very entertaining way of presenting science around many different areas of our metabolism and longevity while also interjecting his dry humor throughout each episode.
  • While Post
    Snake oil
    Big Wellness enters its smug phase.
  • andreawammack
    Ryan Holiday show
    It’s hard to take courage advice from someone who would have you forced to take a vaccine because he thought it was the courageous and right thing to do. Slippery slope if we don’t all know the same facts. He’s a bit tyrannical in his approach I will say. Doesn’t seem very stoic when you actually get him talking
  • Hoochie84
    Unsure
    Listened to the Siggi interview on liver health, & it wound up being an infomercial on their products. So not sure yet of the ulterior motive here?
  • smacko11
    He’s a fraud…
    Can’t take more than a few minutes of this guy’s voice, tone and demeanor. He’s insufferable and know-it-all who is constantly disrespectful to his guests…
  • PrincessPeach81
    Disappointed
    I listened to the interview with Bryan Johnson, where Dave asks him if he’s a nerd and repeatedly bullies him into a corner about being “neurodivergent”. He definitely missed Bryan’s whole point. But I don’t know what I was expecting from someone who claims they “cured” their own Asperger’s syndrome.
  • Justatexter
    Kava
    Just enjoyed this episode and placed orders. Love all Dave’s episodes. I am learning so much.
  • 4jenzo
    Algae Episode 1213
    Love you for years, Dave! Thank you for all you have done for alternative health. But have to say that after this one, I'm confused. You taught me years ago that the fatty acids, beta carotene, b vitamins, etc that are present in algae are not easily absorbed and converted by some people to their utilizable forms. Best to feed the algae to cows, then eat the cows. I'm surprised you let her rattle off her sales pitch, even when she mentioned cows farts and global warming-whaaaat?!?!? You debunked that years ago yet didn't push back. Stay on em, Dave!
  • VanessainNYC
    Host Gets in His Own Way
    The show is very interesting, the guests are very interesting, these podcasts offer so much cutting edge knowledgeable, but the host has a very fragile ego and it’s exhausting to listen to him at times. He has a vendetta towards Peter Attia. He’s sometimes antagonistic towards guests. Why?
  • SexNutritionDoctor
    Solid, Entertaining Info!
    Great stuff. Check it out!
  • chelbellwell
    Episode 1194
    Amazing story! Thanks for providing as always the best content.
  • lakelady16
    The Best Most worthwhile Podcast
    I have been listening to this podcast for more years than I can count and I always learn something new every episode! Dave is kind and intelligent and brings on the most thought provoking guests full of insightful information. I will keep listening for as long as Dave has podcasts!
  • PMJ2323
    Terrible Interviewer
    Podcast has so much potential, but doesn’t ask good questions and can’t stay on track. No flow, always off topic and unorganized. Has such great people on, but doesn’t ever get to the point of the subject.
  • Slumlord 17
    Best info
    Love this show Smart guests Cutting edge idea No add interruptions!
  • BozieOzzie
    Every show is trying to sell you something.
    As the title says, every show either the author or the guest for both are trying to sell you something. Take everything with a grain of salt. They’re not backing up their claims with good research. They’re taking small studies, sometimes not even in humans, and making huge claims that just isn’t supported by the data. I was really looking for a fresh perspective, the one that is evidence based. One thing, however, we can all agree upon is that processed foods in the American diet is harmful.
  • weeded out
    Some Major Snake Oil Shills
    Not sure if he gets kickbacks from certain guests or what but a lot of these personalities/products are curiously bereft of any valid patents or data, yet presented as “experts in the field.” Rich people promoting rich people’s vanity projects ?
  • Rachel3601
    I can’t take the self promotion
    I find this podcast pretty informative but I’m listening to learn from the people mr asprey is interviewing. Instead, you mostly hear mr asprey talking about himself, pimping his products, and commandeering the whole podcast. If you count all his sentences in a podcast, I guarantee that he talks twice as much as the person he’s interviewing. This seems to be a common theme among the popular podcasters lately. I’m just not listening to it anymore.
  • palakini
    Derogatory
    I’m a nutritionist with a a MS in nutrition science. I practice functional nutrition and I am very turned off about your generalized derogatory comments about dietitians. Very Trumpesque! Poor taste. Hard to listen to what you ‘might’ have to say that could have to say with merit.
  • DaveAspreyOnlyWantsYourMoney
    Go elsewhere
    There are way more qualified, way less shilly providers of information out there. I don’t know how to stop seeing this podcast in my feed, so perhaps this review will convince Apple to show me something more worth my time.
  • Leanne Jill
    Couldn’t get through it
    I wish he wasn’t so condescending and arrogant. Had to turn it off after 5 minutes. Was so excited to learn more but just couldn’t get through him interrupting guests with uncomfortable not funny remarks.
  • Nana4170
    Overhaul the American food and pharma system.
    Let’s put all the blame on the food and pharma. Yes they definitely have a role in the declining health of the US. I am speaking as a 75 year old woman who was overweight and pre diabetic at 60. I wasn’t wealthy or do I have a college degree but I had the desire to live longer and be healthy. I have an iPhone with a world of knowledge. I researched and experimented with different diets and soaked in new studies on longevity. Within about 6 months I had lost the weight and was no longer pre-diabetic and am metabolic healthy. Today I have a diet of grass fed beef, pasture eggs and butter etc. No grains or seed oils. Love cooking my nutritious food. I have gently tried to give the info to family and friends some take advice and others refuse to give up their highly processed food. Instead of 100% blame on food and pharma why not some percentage on personal responsibility. FYI couldn’t listen to promoting conspiracy theorists or a lying criminal. Food industry and pharma didn't change I did!!
  • insidemoves
    Tomatis sound therapy
    Great interview. I do sound therapy called Tomatis. I think you know what that is. We hear through both air and bone and when you talk inn-an embodied way your receiver can hear through both ear and bone. Read Dr Tomatis' book the conscious ear
  • tanyaBK
    Awesome podcast
    Before I dived in, I red some reviews and almost didn’t go through with this podcast, but I’m so happy I did in the end cause I can’t stop listening! I thought Dave was arrogant but it’s not that, it’s more like a Charisse’s with dry sense of sarcasm, which I like a lot. And the guests are great! Glad I kept listening as it’s a ton of great info
  • 3rdL
    If you’re ready, you’ve landed ...
    Dave’s style is the absolute best in my podcast listening world (7 years total) I’ve watch the Bulletproof brand get stronger year after year. Dave is brilliant at so many things and thank God he is in this space where we need him. I have gotten immense knowledge from his BP podcast, and now this one which is my go-to for Upgrading my biology. Dave is selective and sets very admirable standards for all of the pieces that make up his bio-hacking endeavors. I have often used his style of integrity as a margin when researching practitioners and products. If you have been in search of this optimal self transformation and human up-leveling, get ready, you’ve landed. ~Lisette, Las Vegas✨
  • Tizzy111www
    Unbearable
    I used to listen to this all the time but Dave’s level of condescension and arrogance makes it unbearable. Was excited to hear his most recent episode with Jessie Inchauspe and literally had to turn it off within the first 10 minutes. I’ll listen to her content on podcasts whose hosts allow her to actually speak without interrupting her every third word.
  • dgustner
    Weary
    So weary of hearing this brilliant biohacker telling vegans they need to see the error of their ways. I am 76 years old and have been vegan for 45 years. I have no chronic disease, no joint pain, no lack of energy. I take no prescription drugs or even over the counter drugs. The last time I was hospitalized was 70 years ago. Last saw an MD over ten years ago. Yet, according to Asprey, I should be severely ill if not dead. The man is obsessed with being right instead of being open to new information if it happens to conflict with his previous assumptions.
  • aprilbeeRN
    Condescending to female guests
    I have listened to Dave before and have bought his products and appreciate the information he shares. After listening to part of the episode with Maggie Berghoff, I will never listen again. I can’t imagine how someone could be so disrespectful and laugh about it.
  • Unity357
    Easy to understand
    I have really enjoyed Dave’s series on Gaia and I find him very easy to listen to and easy to understand. With such in-depth knowledge he also allows his guests to speak. I consider him a honorary doctor in the field of human science and this is an area all humans should explore and self educate.
  • Melinda82785
    No emotional Intelligence
    Advice you need to hear: focus more on being interested and less on trying to be interesting. Elitist, condescending, constant need to “prove” he knows more than a guest. Pay attention - his goal isn’t to inform his goal is to sell you something.
  • radsummer
    Interact with listeners
    It would be nice if Dave Asprey took questions from listeners or provided some kind of a back and forth option with people. Is there a forum anywhere that I might have missed? It all seems very one sided. I just bought something recommended on his show, and while I understand there is good research backing it up, there is also a warning on the bottle for reproductive health- something he did not mention or discuss at all. Also, a lot of the supplements recommended by his show contain other ingredients that might already be taken by listeners, so he also never talks about combining things with what one is already taking. I just wish there was more of a dialogue with listeners if he really wants to be taken more seriously and respectfully. Does anyone know if I can send questions somewhere? Or is this all brushed off under the “sorry not a doctor warning” ?
  • Lkjhag
    Would love more accessible solutions
    This podcast feels elitist. Yes I have only listened to one episode, but it seems that a lot of the information while it is very great and enlightening doesn’t seem applicable to those with certain limitations in their finances and access to certain cares. I left this feeling like there was no solution to the things that I just learned about.
  • Jthe Gent
    some helpful information if you can wade through his ego
    dave should let his guests talk more. he is beyond annoying with his opinions. some are here for facts or different perspectives, even if we don't agree.
  • cfsmiles
    Very informative but….
    Great content and guests but Dave always interrupts and makes it about him.
  • biointel
    thanks Dave
    Simply the best in the field of biotech enlightenment much gratitude to a pioneer in the frontier of human wellness. Perhaps the best source of information I have found.
  • Fitnessnut 62
    Love these podcasts
    Just listened to Dave and Elle Russ. So informative- I always enjoy Dave’s content.
  • Happy🤪girl
    My favorite podcast by a mile
    Cutting edge health info, broken down so it’s understandable, interesting and includes actionable items. I am truly grateful to Dave Asprey for this as well as his perspective on health, longevity and so many important issues of our environment. Now I’ve become that dorky person, always saying “I have a podcast for that!” So glad I found this !!! 😍🙏🏼😃
  • kbryson1
    Super Dave
    I always learn something new each time I listen to this podcast.
  • TLWhiskers24
    Great info
    Dave is the Elon Musk of bio hacking.
  • miley_cyrus_luvar
    Anti vegan
    He makes a full of himself when talking about veganism! Makes me doubt his knowledge about other things!
  • BP Writer
    Fantastic host, consistently great content and guests!
    Came across the Human Upgrade podcast and am loving it! Especially enjoyed the episode about how breast implants can compromise your health and make you sick with Austin-based Dr. Robert Whitfield. This conversation was so candid, transparent, and moving! So many important takeaways! Can’t wait to listen to more episodes! Thank you!
  • tomrunsearth
    I’ve been hacked!
    Hi, my name is Tommy Taylor and I have become a Hack-Aholic ever since my first sip of the Bullet Proof world. I now have over 1,300 hours of Dave in my brain. Mr. Asprey has spent countless hours, funds, and self experiments to achieve maximum performance from a human body. Let’s face it, we were created as pretty awesome creatures-with biological flaws. Such as computers were created with flaws that allow an outside source (viruses) to change the outcome of what it was programmed to compute. In short, he found a way to hack our biological flaws with nutrition, light, bi-feedback and knowledge of the amazing available resources (as well as the ones to avoid) this planet has a lot to offer a mere human to perform at it’s maximum potential. Cheers! Tommy Taylor Hack-Aholic, Ultra-runner, Ironman, surfer, grandfather of four.
  • joanne@redwoodshore
    Great podcast. Very educational and inspirational
    This is my favorite podcast for years. After reading the Super Human book, I started to listen to this pod regularly and bought supplements with discounts. They are very helpful to me. Thank you 🙏
  • garth1k
    MsSSS
    Why do you feel you have to ‘One Up’ everyone of you guests? This is not a competition!
  • C777
    Don’t like this podcast
    This guy is obnoxious and rude.
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