U22 is about readers' journeys through Ulysses, James Joyce’s modernist epic about the lives of ordinary people on a day in Dublin in 1904. The podcast anticipates and accompanies a reader-friendly edition Catherine Flynn is bringing out with Cambridge University Press for the book’s centenary in 2022. Here, she and her co-hosts Rafael Aguilar, Emily Moell, and Louie Poore talk with the contributors to the volume and with readers of Ulysses from around the world. Listen to their first impressions, later realizations, and the challenges and the pleasures they met along the way.